Stem cells are characterized as forerunner cells that have the ability to self-restore and to generate multiple cell types. They have two interesting properties that empower them to do this:

First and foremost, they can divide again and again to create new cells. Also, as they divide, they can change into different types of cells that make up the body.

There are three different types of stem cells. One of them is the embryonic stem cells which supply new cells for an embryo as it grows and develops into a baby. They are pluripotent, which implies that they can change into any cell in the body.

Another one is called adult stem cells. They supply new cells as an organism grows to replace damaged cells. They are multipotent, which implies they can just change into certain cells in the body, for instance:

Epithelial stem cells can only replace the various kinds of cells in our skin and hair.

The last one is called the induced pluripotent stem cells, or IPS cells. They are cultured in the lab by taking normal adult cells, like skin or blood cells, and redesigning them to become stem cells. The fact that they are pluripotent means they can also change into any cell type.

Research into the use of stem cells to repair bones, ligaments, tendons, spinal cord injuries and in the treatment of kidney and liver disease, cardiomyopathies, and certain inflammatory diseases of the skin and gut is ongoing, However, stem cell therapy has been commonly used in the treatment of osteoarthritis and hip dysplasia in pets such as dogs and cats.

The procedure is the same in most clinics that perform stem cell therapy for pets. Generally, once you visit the veterinary doctor, they have to review the condition of your pet (including prognosis) with stem cell therapy. Your pet would be intubated and properly observed and monitored during the procedure.

The stem cell therapy treatment should average three to four hours. An intravenous catheter would be used to administer pet anesthesia and up to two tablespoons of fat are removed from the shoulder or abdomen of the pet. The stem cells are separated from the fat within 48 hours of extraction, and it is ready for infusion into the affected area. Asides from transforming into any cell type, stem cells block the formation of inflammatory molecules and scar tissue, and they signal the body to produce pain-reducing substances.

Improvement is usually noticed within 14 days of treatment. The risk of rejection is eliminated because these pets receive their own cells.

Although it is better for your pets to receive treatment within 60 days of injury, stem cell therapy can also be helpful in improving long term injuries.

There are lots of affordable pet clinics that perform stem cell therapy for pets. If your dog is in need of a stem cell therapy or you are aware of dogs in your neighborhood in need of one, all you need to do is to type the words, dog stem cell therapy near me and include your location using any of your favorite search engines.

Websites, clinic names, and contact details should pop up and from there you can easily pick the one that appeals most to you.

Go here to read the rest:
What are stem cells and why are they important for pets ...

ABCGallant Stem Cells on 'Shark Tank'.

Tonight, Gallant Stem Cell Therapy For Dogs will be featured on an all-new episode of Shark Tank.

The company was founded by Aaron Hirschhorn, and is the first and only non-invasive animal stem cell collection method available today.

Interested in learning more about Gallant Stem Cell Bank? Read on.

Gallant on Shark Tank.

Hirschhorn is the founder and former CEO of DogVacay. The company was launched as an app in 2013 and merged with Rover.com in 2017. It eventually went on to become a $1 billion pet services marketplace.

According to Business Wire, Gallants research team is developing the first-of-its-kind biotechnologies and treatment methods. It is committed to spending millions on R&D pursuing both autologous therapies, which use a dogs own stem cells, and allogenic therapies, which any dog can use, at a fraction of the cost of currently available therapies.

The Gallant team consists of veterinarians, scientists, and entrepreneurs who hold themselves and their lab to the absolute highest standard. Today, they are working with VDA as part of the Veterinary Innovation Program to develop therapies.

A few years ago, Aaron suffered a major back injury. He was forced to undergo stem cell treatment, which worked well. The News Crunch writes, Aaron, being an ardent dog lover wondered why this cutting-edge medical technology of stem cell transplants cannot be applied to dogs.

The company was officially created in 2018. In August 2019, Gallant raised $7 million in investments.

In a statement obtained by Tech Crunch, Hirschhorn said, I struggled with debilitating chronic back pain for more than a decade, leaving me incapable of doing activities I loved, until regenerative medicine successfully cured my condition At the same time, I watched my dog Rocky suffer from arthritis so painful that she couldnt walk. I knew there had to be a better way to treat and heal our pets, which sparked the beginning of Gallant. We are on a mission to keep our pets happier and healthier through the power of regenerative medicine.

GettyKevin OLeary, Lori Greiner and Daymond John on Shark Tank

Gallant works with your personal veterinarian. They collect your pets stem cells so that down the road, [they] can help treat the most common health problems your dog may face.

According to Gallant, a dogs own stem cells have helped with a number of illnesses including osteoarthritis, atopic dermatitis, torn ligaments and chronic dry eye.

Dr. Black, chief scientific officer at Gallant, said in a statement, In my experience with clinical trials and evaluating dogs with debilitating arthritis, Ive seen first hand how cell therapy can change lives Im committed to developing therapies that dramatically improve the quality of life for dogs.

If you head over to the Gallant website, youll find that the company is waiving their $395 processing fee in honor of their Shark Tank debut. They are also offering special pricing a $595 Lifetime Stem Cell Banking plan (typically, this costs $990). Or a $95/year special Shark Tank pricing for the Annual Plan.

They write on their site, Gallant is at the forefront of science, working every day to advance the field of stem cell therapy. By partnering with Gallant, you can make regenerative medicine a part of your pups wellness plan making every (dog) year count.

The company reveals that most dogs begin entering senior age around 7. The effects of aging can be felt as early as 4. Most stem cells are lost over time due to aging, and the procedure to acquire those young stem cells is done young, while the puppy is spayed/neutered. Ahead of the dogs spay/neuter, Gallant connects with your vet to send them a collection kit. During the procedure, the vet then takes out the stem-cell rich reproductive tissue. Stem cells are then acquired and frozen in liquid nitrogen to preserve them. They can be sent to your vet when and if treatment is needed.

What typically happens to the reproductive tissue during a spay/neuter procedure? It is discarded. And its worth noting that traditional methods for injury and age-related conditions are expensive and can have harmful side effects.

GettyHosts Robert Herjavec, Lori Greiner, Daymond John, Kevin OLeary and Executive Producer Clay Newbill of Shark Tank speak onstage during the ABC portion of the 2013 Winter TCA Tour at Langham Hotel on January 10, 2013 in Pasadena, California.

In August, according to the LA Business Journal, two dozen investors contributed to a $7 million funding round. The names of those investors were not given.

Today, Gallant is based in Santa Monica. The company pays veterinarians a commission and encourages them to perform stem cell therapy. According to the site, vets could earn up to $200 to $500 per treatment.

In a nutshell, Gallant is like cord blood banking for your most loyal friend. But will the sharks bite when it comes to Gallant? Tune in tonight on ABC at 9pm ET/PT to find out.

READ NEXT: Dog Threads on Shark Tank: 5 Fast Facts You Need to Know

Read more:
Gallant Stem Cell Bank on Shark Tank: 5 Fast Facts ...

Editor's note: Interviews were gathered last year and reflect that time period in the production process of Wild Type.

Do we need animals to make meat? What if we could grow cells outside the body of an animal to create the food on ourplates? Would we still farm them or would we embrace the alternative?

This is a new era of "clean meat" science, also called "cell-based", lab-grown, or "cultured" meat. It is a way to grow cells into meat rather than feed, breed, and kill the animals in the traditional sense. This is not to be confused with plant-based meats that source plant products in an attempt to reconstruct meat or genetically modifiedfoods that have had theirDNA modified.

"None of us really like the designation [of cell-based]," said Arye Elfenbein, a cardiologist and one of the founders of Wild Type.Every animal is a collection of cells, so the distinction is a bit nonsensical.

The terminology is notchiseled in stone but manybelieve thereis a need to rethink our food system, whether it be in the way we farm, the substitutes we use, or something novel altogether.By 2050, the global population will soar past 9 billion. Annual meat production is projected to rise to 470 million tonnes, according to the Food and Agriculture Organization (FAO) of the United Nations. Fish accounted for around 17 percent of the world'sintake of animal protein in 2013.

The need for alternative food cultivation to reduce the burden on Earths resources is real, but how realistic is clean meat?

A handful of companies are working on making meat or seafood without animals, including Shiok Meats (shrimp) and Avant Meats (fish maw, or the swim bladders of large fish). There are plenty of benefits to be had as well as potential pitfalls to making it happen.

IFLScience talked with Wild Typefounders Ary Elfenbein and Justin Kolbeck in San Francisco as well as Liz Specht, a senior scientist with The Good Food Institute, on the future of the cell-based seafood industry.

Clean Meats And Seafood Poisoning

The mission behind cell-based seafood is to make the cleanest, most sustainable fish on the planet. Cleanest here means no mercury, no sea lice, no microplastics, no antibiotics all of which can be found to varying degrees in farmed and wild beasties.

"Likewise, it is sustainable because we dont have to take any fish out of the sea to make what were doing," said Kolbeck, who previously worked as a diplomat in food insecure regions. "People know that this is the healthiest fish you can find on the planet in that its free of those contaminants."

The overuse of antibiotics is contributingto resistance in humans, with the World Health Organization (WHO) recommending we reduce our antibiotic reliance in farmed animals. In its current stage, this is unlikely to be a problem for cultured meats. Currently, around abillion animalsare slaughtered every year for consumption.Illicit fishing alsoaccounts for around15 percent of the worlds total annual capture fisheries output, according to the FAO.

This is not to say lab-based seafood won't have its own sustainability challenges too, most notably in terms of energy use and scaling up to meet an ever-growing population.However, our current food habits are taking a toll on the planet in the form of habitat destruction, depletion of resources, vulnerable species, among others.

"A 2018 report by the United Nations Food and Agriculture Organization found that one-third of all fish stocks are being depleted faster than they can replenish. Another 60 percent of stocks are fished at the maximum sustainable level, leaving only 7percent of fish stocks that are underfished," according to a report by The Good Food Institute.

The Big Bang For Fish

To produce meat without an animal as a receptacle itself, you have to think backwards. Rather than feeding a full-grown creature, youre feeding a collections of cells to grow into the food on the fork. These muscle cells, fat cells, and other cell types grouped as connective tissue will slowly become the meat you ingest and absorb into your body.

"When you think of the world from the view of the cell, youre trying to encourage the cells to do the same thing it would within the animalsjust outside of the animal," saidElfenbein.

This requires some tinkering to get the environment right just as you would for, say, an animal in a wildlife park, except the enclosure here is steel tanks and petri dishes, not fences and gates. The food these cells love to gobble up are salts, sugars, and amino acids, as well as growth factors to help with proliferation and maturation; the scaffolding and temperature need to hit a happy medium too.

Now you may be wondering why this future of food isnt closer to reality when we have mini brains and 3d-printed body parts. The truth of the matter is that the science of mammalian research is simply further along than cold-blooded vertebrate animals.

"Most of the work on stem cells, molecular biology, and even tissue engineering has been grounded in mammalian research," said Elfenbein.

"Fish being so removed evolutionarily from mammals actually use different genes that then code for different proteins to do the same things in very different ways." Fish cells, for example, can grow in a wide variety of temperatures and tolerate low-oxygen concentrations because they dive deep into the ocean. Not so for mammalian cells.

"We are just learning how to take care of and nurture these cells," added Elfenbein. "Learning what these cells like and what they dont like. People have often likened it to taking care of a pet without being able to directly communicate with it."

What Are The Hurdles?

Cell-based seafoodis a new frontier being explored and with that comes unexpected stumbling blocks."There's still certainly a lot to be learned," said Elfenbein.

One of these is cooking the salmon, which has been presented to consumersraw so far. Wild Type salmon can be cooked, they say, but they're "working on the texture" at the moment.

"There are lots of technical hurdles here to overcome," saidPaul Mozdziak, a muscle biologist at North Carolina State University, to Nature. The challenges include better cell lines and scaffolding materials to shape the cells into tissue. Not only that but often research is kept in-house as trade secrets. There is also the question of labeling and what is required to tell consumers on packaging.

Some say they should just call it "meat", others "cell-based", others "clean meat" or "slaughter-free meat". Scalability for large-scale production is another hurdle Wild Type and other companies are considering. Wild Type has already created raw salmon in a variety of shapes and sizes, with one of their most popular dishes at an Oregon tasting event being the poke bowl and sushi.

"Today, our sushi costs about $200 for an 8 piece sushi roll when were ready to roll it out it needs to be a $6 sushi roll," said Kolbeck.

Others have noted that if it seems gross for meat to be grown in a lab, factory farming too has its considerable share of gross factor. Still, for now it's for the consumer to decide what they are comfortable with.

A literature review of consumer acceptancestudies up to 2017 from the USA, India, and China revealed men are more likely than women to accept cultured meat (except in China where it was reversed), as are those with more education and, surprisingly, those who are meat eaters rather than vegetarians. Overall, China and India were more accepting of clean meat than the USA. The demographic trends were compiled byChrisBryant, a doctoral researcher at the University of Bath.

"This is interesting because omnivores are of course eating vastly more meat than vegetarians (even assuming some vegetarians are less strict than others), and men typically eat about twice as much meat as women, so the groups that are consuming the most meat are the most receptive to cell-based meat," said Specht from The Good Food Institute, to IFLScience.

Some of thechallenges in developingtissues that resemble muscle rather than ground meat may help provide insights further down the line fortissue engineering for regenerative medicine. "Cell-based meat actually offers a much easier task than producing, say, a regenerated organ for transplantation: cell-based muscle tissue doesn't need to be functional it simply needs to have approximately the right structure and therefore texture," said Specht.

"The good news is that researchers can leverage the vast scientific literature and new technologies (faster sequencing, better characterization methods, etc.) to fill in the knowledge gaps for cell culture of seafood-relevant species much more quickly than the time it took to develop these tools and knowledge for mammalian cells," added Specht.

Is it Vegan?

Clean meat is still meat, so it is not vegan in that sense of the word. However, for vegans who avoid meat for health, environmental, or ethical reasons, clean meat could be considered a "vegan option" because there is no sentient animal involved in the production.

"Before weve only had animal or non-animal and now we have animal but not made from an animal, so what is that?" asked Kolbeck. "I think the classic definitions and categories may need to evolve a little bit to be more nuanced."

In theory, the team say they could replicate the nutritional profile of the meat to match that of the original animal,whicharea rich source of proteins andessential amino acids, fats, vitamins (D, A and B), and minerals, particularly if eaten whole.

"There are several research gaps that exist for marine cell culture, alongside several opportunities that make these research gaps worth addressing," writean unrelated team ina recent paper in Frontiers in Sustianable Food Systems."With growing interest in cellular agriculture as a means to produce meat, milk, eggs, and other animal proteins from cell cultures, and with the rapid intensification of aquaculture systems, the time is right to investigate the production of seafood without marine animals."

Continue reading here:
Do We Need Animals To Make Meat? - IFLScience

CALGARY -- New research at the University of Calgary has taken a step toward understanding how skin heals, which could lead to drug treatments to improve healing.

We identified a specific population of progenitor cells that reside within the dermis, the deep connective tissue of the skin," said Jeff Biernaskie, a professor of stem cell biology in the U of C faculty of veterinary medicine (UCVM) and the Calgary Firefighters Burn Treatment Society chair in skin regeneration and wound healing.

"Progenitor cells are unique in that they can undergo cell division and generate many new cells to either maintain or repair tissues."

The new study, led by Biernaskie and published in the scientific journal Cell Stem Cell, was co-led by Dr. Sepideh Abbasi, Sarthak Sinha and Dr. Elodie Labit.

The intensive, five-year study offers new knowledge on why specific dermal cells can regenerate new skin, rather than scar tissue.

According to the news release, genomics techniques were used to profile thousands of cells at different times after injury, followed by the research team comparing scar-forming versus regenerative areas within skin wounds.

Remarkably, we found that although these cells come from the same cellular origin, different microenvironments within the wound activate entirely different sets of genes," said Biernaskie. "Meaning, the signals found within regenerative zones of the wound promote re-activation of genes that are typically engaged during skin development.

"Whereas, in scar-forming zones, these pro-regenerative programs are absent or suppressed, and scar-forming programs dominate."

With these findings, the research team was able to show that its possible to modify genetic ways that control skin regeneration.

What we've shown is that you can alter the wound environment with drugs, or modify the genetics of these progenitor cells directly, and both are sufficient to change their behaviour during wound healing, said Biernaskie.

"And that can have really quite impressive effects on healing that includes regeneration of new hair follicles, glands and fat within the wounded skin.

The next step in this research is developing a drug that would prevent scar formation and improve skin healing.

This proof of principle is really important, because it suggests that the adult wound-responsive cells do, in fact, harbor a latent regenerative capacity, it just simply needs to be unmasked," said Biernaskie.

Now, we are actively looking for additional pathways that may be involved. Our hope is to develop a cocktail of drugs that we could safely administer in humans and animals to entirely prevent genetic programs that initiate scar formation in order to greatly improve the quality of skin healing.

See the article here:
University of Calgary study finds insights in skin regeneration after severe burns or injuries - CTV Toronto

Stem cells are a really trendy subject nowadays, and there are many good reasons why. Theyre the most important key to health, youth, regeneration and anti-aging in humans and animals. In this article, well look at what stem cells are, and what triggers them to heal and repair tissues in our bodies, as well as those of our dogs and cats.

Stem cells are how we all started out. Theyre the cells that develop into the different organs in our bodies when we and our pets are tiny growing embryos.

In mammals, stem cells regularly divide to repair and replace worn out or damaged tissues in the gut and bone marrow. In other organs, such as the pancreas and the heart, stem cells only divide under certain conditions. Without stem cells, wounds would not heal. Blood would not be able to regenerate. In fact, there would be no way to survive.

Stem cells, and the work they do, can vary from species to species. Salamanders can use their stem cells to regrow their tails, yet we humans certainly cant regrow our fingers! Horses and cows have stem cells in their teeth, which replenish throughout their lives. As we and our animals age, however, the function of our stem cells declines.

In many tissues, stem cells serve as an internal repair system, dividing essentially without limit to replenish other cells, as long as the person or animal is alive.

Even after very long periods of inactivity, stem cells are capable of renewing themselves through cell division. Once they become active again, they can renew or replicate themselves for very long periods if they do not become specialized. Unspecialized stem cells can give rise to specialized cells, as they can be induced to change into specific tissues or organs.

Its important to understand that there are different categories of stem cells, depending on their capabilities.

The stem cells in our bodies, and those of our pets, work to regenerate and heal us, but the trick is knowing how to effectively trigger them. Scientists are now beginning to understand the signals that trigger stem cells to get going and start their repair work. These very important signals are carried by special messenger compounds called kinases.

Kinases comprise the repair and regeneration mechanism of the body. They have enormous diversity and play a critical role in cellular communication and signaling. A loss of function in kinases has been proven to cause cancer and other disease in humans. Kinases have the effect of making cells renew and reconstruct themselves. Importantly, they also stimulate and activate stem cells.

Kinases stimulate repair and activate stem cells. They are of ultimate importance to good health.

Drugs such as Apoquel and Cytopoint work to decrease allergic reactions by obliterating specific kinases. Apoquel detrimentally affects several different kinases. Cytopoint advertises that it destroys only one kinase, but as each kinase communicates with literally hundreds of others, obliterating even one has a cascade effect.

We dont preserve umbilical tissue from our dogs and cats, although this may evolve into an industry in the future. Our animals fat cells can be cultured to make stem cells, which are limited to forming connective tissue only. And as we and our pets age, the stem cells in our bodies become less vigorous.

Nevertheless, many products are being touted as stem cell activators. Whether all these products actually work is debatable. Cosmetic companies offer topical solutions to make your skin young again. Specific oral supplements claim the ability to activate stem cells. In fact, stem cells has become a buzz phrase to increase interest and sales. Its being overused and generalized, and there are so many stem cell-activating products out there that researching every single one for efficacy would prove a daunting task.

However, for about four years, I have been successfully using stem cell-activating products made in France and approved for use in the United States. These products are not at all like the stem cells derived from a pets fat. They are not made from self but are created to target a disease in order to mend, improve or cure it. These products, in addition to cells from the placenta and umbilical cord, contain cells to direct healing to the targeted organ, along with superoxide dismutase, glutathione reductase, glutathione transferase, glutathione peroxidase, and kinase activators to increase communication within all body systems.

I have used these products (made by Biocell) for many different cases. For example, I have seen routine success using them in cats with FIP and lymphosarcoma. Amazingly, when these patients return to heath, they are actually cured. Remember, we are not using fat cells from the individual animal, which would be contraindicated in cancer these are stem cell-activating products. Cure is achieved by activating the patients immune system and thymus gland. We are simply activating the patients own stem cells, which then work to cure what are considered incurable diseases.

The importance of the kinase communicators in our pets bodies cannot be underestimated. Thanks to them, an intricate and perfect system designed to maintain health at its best exists in every human and animal body. Working with that system constitutes holistic medicine in its purest form. In general, holistic modalities work to create a stronger, wiser and healthier body. Giving stem cells a nudge getting them off the couch and back to work produces a potent healing effect. For me, using stem cell-activating products for healing is extremely rewarding.

More:
Stem cells and your pet | Animal Wellness Magazine

Overview

Stem cells found in the fat tissue of dogs are adult stem cells that have the ability to differentiate into many different cell types. When there is an injury or inflammation, the body naturally recruits the type of cells it needs to help with healing. When you introduce stem cells in that situation, your dog or cats body develops them into their type of cell needed for that injury.

To use stem cells, your pet would undergo a brief period of anesthesia so that a small amount of fat can be surgically removed. The fat sample is then processed to isolate and activate the stem cells. The result is a solution of concentrated active stem cells that can be injected into your pet to speed and improve healing.

Stem cell therapy is most commonly used for osteoarthritis and ligament/tendon injuries. Recently, there have been cases showing its effectiveness for degenerative myelopathy, spinal trauma, gingivitis/stomatitis, inflammatory bowel disease, certain autoimmune conditions and even liver and kidney disease.

Platelets are a component of blood that are best known for allowing wounds to clot. These platelets also contain certain proteins and growth factors that can kick start tissue healing and decrease inflammation. PRP is a concentrated dose of these beneficial components.Platelet rich plasma starts by taking a sample of blood from your pet. That sample is spun in a centrifuge in a special collection tube that allows the extremely platelet dense portion to be separated from the rest of the blood. The PRP sample can then be injected into your pets injured joint or made into a gel that can be applied to wounds or burns.

One of the biggest benefits of stem cell and PRP treatments is that they can reduce or eliminate your pets need for pain medications and non-steroidal anti-inflammatory drugs (NSAIDs). These drugs can have adverse side effects or are not safe for pets with certain disease conditions. Since both the stem cells and PRP come from your own pet, there is no risk of reaction or adverse effects. Stem cells can also be banked or stored at the processing facility so if your pet needs additional injections in the future, he/she will not need to undergo another collection procedure.

For more information on Stem Cell Therapy and PRP, check outMediVet Biologicswebsite athttp://medivetbiologics.com/home/pet-ownersor call 386-761-2220 and schedule an appointment withDr. Zukerto discuss how these treatments can benefit your pet.

View original post here:
Stem Cell Therapy | Atlantic Animal Hospital

Two injections containing about five million stem cells delivered directly to Brodys hip jointsDuring last months surgery to address an issue with Brodys joints, Dr. Jeffrey Christiansen of Superior Veterinary Surgical Solutions collected a small amount of Brodys fat. (Brevard Zoo image)

BREVARD COUNTY MELBOURNE, FLORIDA During last months surgery to address an issue with Brodys joints, Dr. Jeffrey Christiansen of Superior Veterinary Surgical Solutions collected a small amount of Brodys fat.

A laboratory extracted stem cells from the fat sample, which can be used to reduce pain and inflammation and promote healing of the surgical site.

On Friday morning, Brody was brought back to the L3Harris Animal Care Center to receive his first dose of this medication.

Two injections containing about five million stem cells each were delivered directly to Brodys hip joints. To accomplish this, Dr. Christiansen carefully inserted a needle into Brodys hip and drew a small amount of joint fluid to confirm the tip was in the right place, then administered the injection.

A third, less-concentrated injection was delivered intravenously.

We also captured some radiographs to check on Brodys hip condition.

While we wont be able to evaluate the long-term effectiveness of the surgery for quite some time, he appears to be recovering without complication.

Brody woke from the anesthesia and was returned to his habitat. It is normal for animals to experience discomfort and lameness for a few days following stem-cell injections, but Brody is already back to being his normal, energetic self.

We have enough stem cells banked for an additional 15 doses, which will be administered throughout the course of Brodys life as needed.

Quality veterinary care is expensive. Click here to support animal wellness at the Zoo during this financially challenging time.

CLICK HERE FOR BREVARD COUNTY NEWS

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Brevard Zoo's Bear 'Brody' Received Radiographs and Underwent First Round of Stem-Cell Therapy - SpaceCoastDaily.com

Canine Stem Cell Therapy Market research is an intelligence report with meticulous efforts undertaken to study the right and valuable information. The data which has been looked upon is done considering both, the existing top players and the upcoming competitors. Business strategies of the key players and the new entering market industries are studied in detail. Well explained SWOT analysis, revenue share and contact information are shared in this report analysis.

The global Canine Stem Cell Therapy Market size is expected to Expand at Significant CAGR of +4% during forecast period (2020-2026).

The non-invasive stem cell obtaining procedure, augmented possibility of accomplishing high quality cells, and lower price of therapy coupled with high success rate of positive outcomes have collectively made allogeneic stem cell therapy a preference for veterinary physicians. Moreover, allogeneic stem cell therapy is 100% safe, which further supports its demand on a global level.

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Top Key Vendors of this Market are:

VETSTEM BIOPHARMA, Cell Therapy Sciences, Regeneus, Aratana Therapeutics, Medivet Biologics, Okyanos

Various factors are responsible for the markets growth trajectory, which are studied at length in the report. In addition, the report lists down the restraints that are posing threat to the global Canine Stem Cell Therapy market. It also gauges the bargaining power of suppliers and buyers, threat from new entrants and product substitute, and the degree of competition prevailing in the market. The influence of the latest government guidelines is also analyzed in detail in the report. It studies the Canine Stem Cell Therapy markets trajectory between forecast periods.

The report provides insights on the following pointers:

Market Penetration:Comprehensive information on the product portfolios of the top players in the Canine Stem Cell Therapy market.

Product Development/Innovation:Detailed insights on the upcoming technologies, R&D activities, and product launches in the market.

Competitive Assessment: In-depth assessment of the market strategies, geographic and business segments of the leading players in the market.

Market Development:Comprehensive information about emerging markets. This report analyzes the market for various segments across geographies.

Market Diversification:Exhaustive information about new products, untapped geographies, recent developments, and investments in the Canine Stem Cell Therapy market.

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The report summarized the high revenue that has been generated across locations like, North America, Japan, Europe, Asia, and India along with the facts and figures of Canine Stem Cell Therapy market. It focuses on the major points, which are necessary to make positive impacts on the market policies, international transactions, speculation, and supply demand in the global market.

Global Canine Stem Cell Therapy Market Segmentation:

Market Segmentation by Type:

Allogeneic Stem CellsAutologous Stem cells

Market Segmentation by Application:

Veterinary HospitalsVeterinary ClinicsVeterinary Research Institutes

Table of Contents

Global Canine Stem Cell Therapy Market Research Report 2020 2026

Chapter 1 Canine Stem Cell Therapy Market Overview

Chapter 2 Global Economic Impact on Industry

Chapter 3 Global Market Competition by Manufacturers

Chapter 4 Global Production, Revenue (Value) by Region

Chapter 5 Global Supply (Production), Consumption, Export, Import by Regions

Chapter 6 Global Production, Revenue (Value), Price Trend by Type

Chapter 7 Global Market Analysis by Application

Chapter 8 Manufacturing Cost Analysis

Chapter 9 Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10 Marketing Strategy Analysis, Distributors/Traders

Chapter 11 Market Effect Factors Analysis

Chapter 12 Global Canine Stem Cell Therapy Market Forecast

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Canine Stem Cell Therapy Market to Witness Stunning Growth to Generate Massive Revenue During Forecast 2020 2026 | VETSTEM BIOPHARMA, Cell Therapy...

KUANTAN, MALAYSIA (REUTERS) - Some skin, eggs and tissue samples are all that remain of Malaysia's last rhino, Iman, who died last November after years of failed breeding attempts.

Now scientists are pinning their hopes on experimental stem cell technology to bring back the Malaysian variant of the Sumatran rhinoceros, making use of cells from Iman and two other dead rhinos.

"I'm very confident," molecular biologist Muhammad Lokman Md Isa told Reuters in his laboratory at the International Islamic University of Malaysia. "If everything is functioning, works well and everybody supports us, it's not impossible."

The smallest among the world's rhinos, the Sumatran species was declared extinct in the wild in Malaysia in 2015.

Once it had roamed across Asia, but hunting and forest clearance reduced its numbers to just 80 in neighbouring Indonesia.

Iman, 25, died in a nature reserve on Borneo islandfollowing massive blood loss caused by uterine tumourswithin six months of the death of Malaysia's last male rhino, Tam.

Efforts to get the two to breed had not worked.

"He was the equivalent of a 70-year-old man, so of course you don't expect the sperm to be all that good," said Mr John Payne of the Borneo Rhino Alliance (Bora), who has campaigned for about four decades to save Malaysia's rhinos.

"It was obvious that, to increase the chances of success, one should get sperm and eggs from the rhinos in Indonesia. But right till today, Indonesia is still not keen on this."

Indonesia's environment ministry disputed accusations of cross-border rivalry as a reason why Malaysia's rhinos died out, saying talks continue on ways to work with conservationists in the neighbouring South-east Asian nation.

"Because this is part of diplomatic relations, the implementation must be in accordance with the regulation of each country," said MsIndra Exploitasia, the ministry's director for biodiversity conservation.

The Malaysian scientists plan to use cells from the dead rhinos to produce sperm and eggs that will yield test-tube babies to be implanted into a living animal or a closely related species, such as the horse.

The plan is similar to one for the African northern white rhinoceros, which numbers just two. Researchers in that effort reported some success in 2018 in producing embyronic stem cells for the southern white rhino.

But the process is still far from producing a whole new animal, say Dr Thomas Hildebrandt and Dr Cesare Galli, the scientists leading the research.

And even if it worked, the animals' lack of genetic diversity could pose a threat to long-term survival, Dr Galli told Reuters.

Indonesian scientist Arief Boediono is among those helping in Malaysia, hoping success will provide lessons to help his country's rhinos.

"It may take five, 10, 20 years, I don't know," Dr Arief added."But there has already been some success involving lab rats in Japan, so that means there is a chance."

Japanese researchers have grown teeth and organs such as pancreas and kidneys using embryonic stem cells from rats and mice in efforts to grow replacement human organs.

For now, however, Iman's hide will be stuffed and put on display alongside Tam's in a Borneo museum.

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Stem cells give hope for revival of Malaysia's extinct rhinos - The Straits Times

(The seventh death anniversary of Deshamanya Gen. Dennis Perera fell on 11 August. This is the Dennis Perera memorial oration 2016 delivered by Air Chief Marshal Gagan Bulathsinghala RWP, RSP, VSV, USP, Mphil, Msc, FIM(SL)ndc, psc, Former Commander of the Air Force and Ambassador to Afghanistan)

The former US President and Supreme Commander Allied Expeditionary Forces in WW 2, Gen. Dwight D. Eisenhower states:

The supreme quality for leadership is unquestionable INTEGRITY.

Without it, no real success is possible;

No matter whether it is on a section, gang, a football field,

In an army or in an office!

Reflecting on the illustrious career of the late Deshamanya Gen. Dennis Perera, one sees an outstanding leader whose lifetime principle was integrity of the highest order personifying exemplary moral courage to do what is needed and what is right, while being an officer and gentleman, par-excellence.

The young Master Dennis Perera was educated at St. Peters College, Colombo, and excelled as a multifaceted student both in academics and sport. In 1949, at the age of 19, he answered the call to the profession of arms to join the then young Ceylon Army.

Young Master Dennis Pereras mothers dream was for her son to a join the order and become a Priest, due to her strong faith in religion. However, an uncle of Master Perera, who was in the Ceylon Police, saw him more as soldier material and convinced his parents to let him join the Ceylon Army.

General Perera received his initial military training at Mons Officer Cadet School, UK, and the Royal Military Academy Sandhurst. He was also a graduate of the British Armys Staff College, Camberley. In 1977, at the age of 46, he was bestowed the twin honours of being the first Engineer officer and also the youngest officer ever to be made the Commander of the Sri Lanka Army. Further the late Gen Perera was an alumni of the prestigious National Defence Collage of India.

On retirement, Gen. Perera continued to serve the nation and the corporate sector, first as the High Commissioner to Australia, and later as Chairman of the Securities Exchange Commission, and as Chairman of Ceylon Tobacco Company, and two other high performing Companies. In the year 2000, acknowledging his meritorious service to the nation he was bestowed the title, Deshamanya. He was next elevated to a Four Star General, in the year 2000.

Gen. Perera possessed a unique character and was known for his compassion and inspiration towards the people around him. He was well known to be a shrewd strategist and a sound leader who always lived up to the motto of the Royal Military Academy Sandhurst, Serve to Lead. Gen Perera maintained the highest level of integrity as an Officer and remains a role model for officering in the armed forces of Sri Lanka. As an officer, and a statesman, he made an everlasting impression for the military fraternity and the nation.

In 2010, I had an interesting experience when I flew with Gen. Perera and his gracious Lady to attend the golden Jubilee celebrations of the National Defence College, New Delhi. Though he had hung up his uniform, some time back, I felt the he remained a hard core General, the way he expressed his thoughts on military traditions. Every conversation, I had with Gen. Perera, made me feel proud as a military officer. It was very apparent that he was most upright and proud of the profession of arms. He professed that a military officer should never lean against any one or be a shadow to any one, and must stand up firm for what is right.

I am very confident that this august audience needs no elaboration on Gen. Pereras role in establishing the KDU. Gen. Perera pioneered and triggered the conversion of the Kandawala Estate into the esteemed Military University it is today.

It was indeed fitting that Gen. Perera himself was appointed the first Chancellor after it became a University. Gen. Dennis Pereras visionary leadership and foresight provided our Army with the Commandos and the Womens Corps as integral units, in corporate parlance two timely investments that have brought rich dividends.

The Association of Retired Flag Rank Officers (ARFRO), which has brought us together this evening, was another successful effort of Gen Dennis Perera. This is the professional institution of the profession of arms in Sri Lanka. It is a member of the esteemed Organization of Professional Associations of Sri Lanka and is affiliation to the World Consultative Association of Retired Generals, Admirals & Air Marshals. A truly worthy outfit to be in, for military veteran of Flag rank after a retirement.

Ladies and gentlemen, Gen. Dennis Perera, was a passionate leader, a visionary and a professional, whose life is worthy of celebration at the highest level of esteem and appreciation.

Considering the epitome of military officering in Sri Lanka whom this oration is dedicated to, I chose as my discourse the obvious attributes practiced by him.

General Collin Powell, the former US Secretary of State said:

The most important thing I learned is that soldiers watch what their leaders do. You can give them classes and lecture them forever, but it is your personal example they will follow.

Ladies and gentlemen, from the very beginning of civilization, when mankind engaged in war fighting, the officer was the nucleus and the pivot around which the rank and file rallied for guidance, direction and leadership. Thus, an officer with firm, coherent decisional ability and robust leadership becomes important for the structural integrity of any military unit.

The contemporary armed forces are ramping up their efforts to groom a capable breed of officers to lead and confront the asymmetric threats encountered by nations in battle spaces which are not clearly defined. It is the need of the day that this effort should persist from the moment an officer joins, as it is only knowledge and its continuous application that will make one perfect.

In this context I would like to quote from Aristotle

We are what we repeatedly do; Excellence, therefore, is not an act but a habit.

For any military officer, Integrity is the primary attribute which strengthens his moral fiber to control emotions, both in times of adversity and success. Integrity is a leadership attribute discussed at length in our profession.

Integrity is defined as, The quality of truthfulness, honesty and maintaining of moral standard.

Integrity then should not be considered a mere attribute, but a virtue to live by for any officer.

The world today discusses and studiously studies Ethics in all spheres public, corporate, national and international. Similarly the military today has been rediscovered around an ethical compass, thus military leaders need to be aware of the dramatic lift in the bar of standards in accountability, honesty, and trust.

An officer is entrusted with; state secrets relating integrity of a nation and the lives of the public and the men he leads. If an officer is found to be dishonest or disloyal, it means that his character has two sides and one will manifest to suit the circumstance, to meet his personal liking and not the common goal.

The officers as leaders must demonstrate the moral fiber to be selfless to address the needs of their subordinates before their own, and possess the integrity to seek wholesome solutions.

Our great nation expects complete honesty and integrity from us; upon which it has entrusted its security and integrity and given us all which have said we needed to do the job. Anything less, if delivered will ultimately put our nation at risk by sabotaging its future, and its strategy to compete in the world. Therefore General Eisenhowers edict that Integrity is the supreme quality of leadership is underscored with no doubt.

Even though midway, I need to make a disclaimer that I will generalize in relation to gender and refer to military personnel as HE or HIM, only to make life easier for me in this discourse and in no way lessen the immense contribution of the ladies in our profession. Professionalism is the next attribute of officering that I endeavor to relate to.

General Charles De Gaulle (Galle), the decorated French Soldier and President describes the men of our profession as:

Men who adopt the profession of arms submit to their own free will to a law of perpetual constraint of their own accord.

If they drop in their tracks, if their ashes are scattered in the four winds that is all part and parcel of their job.

The contemporary military culture is far distanced from the traditional forms of war fighting, as cyber space, smart equipment and proactive tactics have encroached at a rapid pace.

However, technology cannot and will not replace the concept of professional officering. Thus the military needs a corps of highly skilled technology savvy officers to command them in tomorrows uncertain environment.

On the other hand, the knowledge of common affairs and skill that is expected from an officer cannot be obtained only by referring to a stack of books and manuals only. It is cumulative, and gained through hard experiences learnt through failures and the continuous attempts to succeed.

The men, the officer of today is called upon to command, are technology savvy, well educated, well socialized and have grown up in a free thinking environment. To be able command their respect and followership one needs to prove professional ability beyond doubt.

The opponents of peace the officer of today will be called upon to confront, are shrewd exponents of asymmetric warfare and are capable of exceptional cruelty and violence as well as, well strategized operations. They have learned and trained to exploit technology and the human mind, with much precision and process to achieve their sick ideological objectives.

Their standard modus operandi is to attack the social fabric at the same time from many directions.

In this context it is imperative for the officer who leads from the front to develop knowledge and all round capacity that includes outside ones lane knowledge.

Ladies and gentlemen, at the end of the day, the most important and cardinal characteristic a professional needs to have is the knowledge and competence in ones own field.

The legendary Field Marshal Sam Manekshaw, of the Indian army has once said:

.. you cannot be born with professional knowledge and professional competence even if you are a child of Prime Minister, or the son of an industrialist or the progeny of a Field Marshal. Professional knowledge and professional competence have to be acquired by hard work and constant study.

In addition to the explicit and tacit knowledge an officer is armed with, he also needs to have an inner thirst and passion for knowledge for things unknown and things outside the zone of comfort. For this the officer needs to be enthusiastic in the never ending process of developing new skills and acquiring new knowledge.

Due to the uncertainty, the high stress levels, and the continuously evolving threats to the society he serves, an officers professional competence must be at the highest level at all times.

For this it is necessary, that the appropriate candidates only be selected to hold the commission, and the aspects of their selection, training, assigning and evaluation, given the highest precedence of priority by the authorities concerned. Incompetent and unprofessional officers, who are unsuitable to lead men and incapable of rational decision-making, should not be tolerated in any military institution.

The popular edict goes on to say that there are no bad soldiers but only bad officers

Professionalism for an officer is not only knowing the job, but it also relates to the discipline and decorum that he and his men maintain while engaged on the task, whatever the circumstances may be. This goes beyond an officer inspecting haircuts, and turn out and bearing but reaches out to greater depth of intervening into unprofessional conduct, such as human rights abuses, or even fraternization. Both these occur due to the lack of self-control and the moral fiber to control ones emotions and is a failure that should be purged from the professional officer corps at the first hint of existence.

In this context, it is the conduct of the officer that the men will follow, and this will then decide, the esteem of the unit in the social domain it operates.

As per the Sri Lanka Air Force Ethos, Core Values and Standards adopted from the Royal Air Force, it applies the following test to determine the code of social conduct.

Have the actions or behaviour of an individual adversely impacted, or are they likely to impact, on the efficiency or operational effectiveness of the Sri Lanka Air Force?

This test applies to all individuals of the SLAF, on or off duty, in order to undermine unprofessional behaviour without hesitation. As far as the social fabric surrounding the Sri Lankan military is concerned.

I strongly believe that this self-query can be applied to any service institution. In the Sri Lankan post conflict environment, where we experience numerous cynical and false expressions, relating to our past and present conduct, it is the leadership that must emerge with professionalism. For this the cornerstone of professionalism must be invented upon good order, discipline, decorum, and exemplary conduct. If our profession loses the trust and confidence of the societal domain, due to unprofessional conduct, it becomes increasingly difficult to acquire the much needed popular support for the conduct of our core competency. Therefore, we must bear in mind that we as officers are responsible for the publics perception of our institutions.

From professionalism I now delve into Empathy, the softer and lesser discussed attribute in an officers repertoire.

General Omar Bradley better known as the soldiers general during WW2 in one of his papers on Leadership states;

A leader should possess human understanding and consideration for others. Men are not robots and should not be treated as though they were machines. I do not by any means suggest coddling. But men are highly intelligent, complicated beings who will respond favourably to human understanding and consideration. By this means, their leader will get maximum effort from each of them.

Knowing your men and to possess the ability to understand and share their feelings are essential empathetic traits of a leader. It is important to develop a memory for names and faces of the people under ones command. The saying goes, a mans name is to him the most important word in his language. Our subordinates endure great pains emotionally, psychologically, physically and socially during war and during peace.

For an officer to mitigate the emotional pain, the officer needs to be able to empathize and make the man feel that his pain is felt even though not necessarily shared or the issue resolved. The approach to resolving subordinates emotional issues is often confounding as only the manifestation is seen.

Human and social issues faced by our subordinates cannot be resolved by the mere application of military law or generous distribution of welfare items to families of subordinates. The genuine caring nature and the ability to feel subordinates pain and see their point of view even though not necessarily accepted are the qualities of an empathetic leader.

Thus, empathy, is an integral part of officering as our subordinates, are constantly exposed to multifarious and intense stressors.

If we carefully review history we see the empathetic side of leaders who were ruthless in the execution of war.

Field Marshall Erwin Rommell the legendry Dessert Fox of the Africa Korps, is known to have been greatly loved by his men and respected by the enemy; he is said to have looked after his men well and grieved at their loss, It is also said that he ignored orders from Nazi leadership to summarily execute prisoners of war.

When an officer is aware of the emotional state of his men, it creates an unspoken bond of trust between them and the officer. Without empathy and compassion ones subordinates will always keep their guards up and be cautious and will have less camaraderie towards their leader.

General George S. Patton, better known by men as ole blood an guts is quoted in the book War as I knew it

Officers are responsible, not only for the conduct of their men in battle, but also for their health and contentment when not fighting. An officer must be the last man to take shelter from fire, and the first to move forward.

Throughout my discourse I have elaborated on three core attributes that are the Ethos of Officering, Integrity, Professionalism, and Empathy. The thresholds of these three attributes converge in most instances supporting one and other.

These three attributes taken in broader sense encompass all values that we would like a leader of our choice to possess. It is not rationally possible for a single human being to possess all three values in their entirety, but we as seniors need to emphasize the importance of these attributes to our younger generations.

As I said, our younger generations have grown up in a free thinking environment and tend to refer to the words realism and pragmatism instead of values. It is in this sense that we need to create awareness of the importance of means as well as the successful achievement of the end It is here that the Ethos of officering comes into bearing.

In the SLAF we have recently introduced the booklet ETHOS & CORE VALUES in this we have translated our values into a broad statement.Through this statement our intention is to give the officer an identity based on value and say this is who I am. At this point I must acknowledge that this book is based on an inheritance from The Royal Air Force but has been remodeled to suit our needs, our culture, and our own values.

The art of officering has evolved in many ways to suit the trends of change, but there are many unwritten laws, traditions, customs, and a value based system of officering handed down by our forefathers of this profession that our generation will now hand over to the next. Men and technology will come and retire but these value based traditions cannot be changed nor should review be attempted, as they stem from valuable lessons learnt from engagement in painful conflict.

Integrity, professionalism and empathy are the attributes that serve as the pillars of genuine officering, they need to be taught, nurtured, developed and appreciated when practiced. This will ensure that the respect and esteem of our sacred profession will remain intact.

May the Late Deshamanya Gen. Dennis Perera be remembered by the future generation for his excellence in soldiering!

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'Integrity, professionalism and empathy, the ethos of officering' - The Island.lk