Veterinary healthcare from your pets point of view

Clickbelow towatch our 2-minute video where Dr. Chris Lee explains our unique philosophy:

Pet Universe Vet Adelaide is a family-run veterinary clinic that has been operating for over 10 years in Adelaides northern suburbs. We offer a range of services to improve your pets health and wellness including:

Our vet centre is friendly, caring and professional, helping to ease your pets fears and your own. On top of excellent veterinary care, we also provide relaxing background music, gentle handling, an optimum pain-relief policy and lots of treats & fuss!

Pets can fall sick at any time. So to offer quality care, our Broadview veterinary clinic is now available for appointments 7 days a week. You can book with me or any of my associates at Broadview or at our Northgate vet practice (open 6 days a week). Contact us at Pet Universe when you need a trusted vet Adelaide.

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Vet Adelaide | Quality Veterinary Healthcare | Pet Universe

At Cell Therapy Sciences we harness the regenerative properties of mesenchymal stem cells to prepare clinical therapies for dogs and horses. Based on our own research, we have optimised these therapies to ensure you receive the very best cells for your patients.

From a small piece of an animal's own tissue, many millions of regenerative cells can be grown by culture-expansion in our specialised VMD-authorised laboratory. We have developed our own, evidence-based procedures for harvest, implantation and transportation, which are simple and practical for vets - and ensure the highest possible standards of safety and quality for pets.

The Evidence Base?

Culture-expanded, mesenchymal stem cells (MSCs) have been used to treat lameness, pain and degenerative joint problems in dogs and horses for more than 10 years. The most recent clinical evidence includes a number of significant, well controlled and large clinical investigations into canine OA (e.g. Shah et al 2018; Harman et al 2016) with authors reporting that MSCs can not only reduce pain and inflammation, but also improve quality of life and enhance tissue repair. The World Small Animal Veterinary Association recognises stem cells in their pain management protocol and include stem cell injectionsfor DJD in dogs and cats in their Pain Council Guidelines.

Why use our culture-expanded stem cells?

We are the most experienced companion animal stem cell laboratory in the UK, having prepared > 2,000 stem cell treatments for intra-articular and intravenous use in client-owned dogs and cats.

We conduct our own laboratory research and have ongoing scientific collaborations with leading stem cell centres, including University College London, Stem Cells Scotland and Coventry University.

Four clinical investigations to date in moderate to severe canine OA have reported significant reductions in pain and improvements in functional mobility following intra-articular injections using our stem cell preparations. These include the first reported study to use two validated arthritis questionnaires to evaluate clinical outcomes in OA (Armitage et al 2018).

Our VMD-authorised cryogenic storage and transport system maximises stem cell quality and viability at point of care and has been shown to be superior to shipping at ambient temperatures.

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Cell Therapy Sciences

Active Comparator: Bortezomib + Lenalidomide + Dexamethasone (VRd) and Rd

Participants will receive bortezomib 1.3 milligram per square meter (mg/m^2) as subcutaneous (SC) injection twice weekly on Days 1, 4, 8, 11 for Cycles 1 through 8 (each cycle is of 21 days); lenalidomide 25 mg orally on Day 1 to Day 14 for Cycles 1 through 8 and on Days 1 to 21 for Cycle 9 (cycle of 28 days); dexamethasone 20 mg orally or intravenously on Days 1, 2, 4, 5, 8, 9, 11, 12 for Cycles 1 through 8 and 40 mg on Days 1,8, 15 and 22 during Cycle 9 and beyond (each cycle is of 28 days) followed by lenalidomide-dexamethasone (Rd) until disease progression or unacceptable toxicity.

Bortezomib 1.3 mg/m^2 will be administered by SC injection twice weekly on Days 1, 4, 8, and 11 of each 21-day cycle for Cycles 1-8.

Other Name: Velcade

Lenalidomide will be self-administered at a dose of 25 mg orally on Day 1 to Day 14 for Cycles 1 through 8 and on Days 1 to 21 for Cycle 9 and beyond until disease progression or unacceptable toxicity whichever occurs first.

Other Name: Revlimid

Dexamethasone will be self-administered orally, 20 mg on Days 1, 2, 4, 5, 8, 9, 11, 12 of each 21-day cycle for Cycles 1-8. During Cycle 9 and beyond dexamethasone, will be self-administered orally at a total dose of 40 mg on Days 1, 8, 15, 22 of each 28-day cycle.

Participants will receive daratumumab 1800 mg as SC injection once every week for Cycles 1 to 2, then every 3 weeks for Cycles 3 through 8 and every 4 weeks for Cycle 9 and beyond; bortezomib 1.3 mg/m^2 as SC injection twice weekly on Days 1, 4, 8, 11 for Cycles 1 through 8 (each cycle is of 21 days); lenalidomide 25 mg orally on Day 1 to Day 14 for Cycles 1 through 8 and on Days 1 to 21 for Cycle 9; dexamethasone 20 mg orally or intravenously on Days 1, 2, 4, 5, 8, 9, 11, 12 for Cycles 1 through 8 and 40 mg on Days 1,8, 15 and 22 during Cycle 9 and beyond followed by daratumumab-lenalidomide-dexamethasone (DRd) until disease progression or unacceptable toxicity.

Daratumumab (1800 mg) will be administered by SC injection once every week for Cycles 1 to 2, then every 3 weeks for Cycles 3-8. For Cycle 9 and beyond, participants will receive daratumumab 1800 mg SC once every 4 weeks until documented disease progression or unacceptable toxicity.

Bortezomib 1.3 mg/m^2 will be administered by SC injection twice weekly on Days 1, 4, 8, and 11 of each 21-day cycle for Cycles 1-8.

Other Name: Velcade

Lenalidomide will be self-administered at a dose of 25 mg orally on Day 1 to Day 14 for Cycles 1 through 8 and on Days 1 to 21 for Cycle 9 and beyond until disease progression or unacceptable toxicity whichever occurs first.

Other Name: Revlimid

Dexamethasone will be self-administered orally, 20 mg on Days 1, 2, 4, 5, 8, 9, 11, 12 of each 21-day cycle for Cycles 1-8. During Cycle 9 and beyond dexamethasone, will be self-administered orally at a total dose of 40 mg on Days 1, 8, 15, 22 of each 28-day cycle.

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A Study Comparing Daratumumab, VELCADE (Bortezomib ...

In December 1988 Sarah Smith was in a serious car accident. Sarah became paralyzed from the waist down. She seldom felt nerves in her legs and feet when touched or tested and she could not walk or stand. The muscles in her hands had atrophied, making it impossible for her to open them. Sarahss health gradually got worse due to lack of exercise and movement. In essence she lived in a motorized wheel chair. After reading an article Sarah contacted the Rehabilitation Institute of Detroit, Michigan. Following grueling tests and therapy Sarah flew to Beijing, China and received Olfactory Ensheathing cell surgery. They implanted stem cells above and below the injured portion of her spine. Immediately she could feel a reaction. Her legs were tingling with sensation. Her right hand opened and closed. Today she is in a manual wheel chair and can kick both legs. With adequate knowledge of stem cell research, learning the benefits acquired through stem cell therapy, and recognizing that support for stem cells is on the rise; it is apparent that even though people believe it is against the laws of God, the positive medical benefits resulting from stem cell research out weigh the negative social penalties.

Due to confusion and general lack of knowledge stem cell research is sometimes wrongly thought of as unethical. Stem cells are model cells found all through the body that have the ability to possess concentrated roles. These cells are grown to imitate blood, bone, brain, or skin cells among others (Heled, 2008). There are different kinds of stem cells deriving from different areas that produce different results. Embryonic or fetal stem cells are believed to be the most influential and controversial in stem cell research. According to the American Journal of Health Education, (embryonic stem cells) can differentiate into almost any type of cell that makes up the body (2008). They originate from four different places: existing stem cell lines, aborted or miscarried fetuses, discarded embryos from fertilization, or cloned embryos. Adult stem cells are harder to manipulate; however, they do offer great insight into stem cell research. Adult stem cells can be found in different parts of the brain and bone marrow (Eve, Marty, McDermott, Klasko, Sanberg, 2008). Because of federal funding there is more adaptability with adult stem cells making them more available. Placental or umbilical cord blood stem cells contain a smaller level of stem cells, but have resulted to be beneficial in the treatment of different disorders. Current research of these cells has brought about encouraging possibilities, but as with all new ideas it does need to be explored more. Stem cell research and the cloning of humans and animals is not the same thing. The cloning of humans to full term is banned more or less across the globe. In some cases short term cloning was performed to allow for the creation and mining of stem cells; however, following the tests the cloned embryos were terminated (Eve, Marty, McDermott, Klasko, Sanberg, 2008). World wide a handful of animals have been cloned, but were inundated with problems resulting in tighter restrictions on human stem cell research. Recent research on cloned animals implies that the duplicated cells do not restart their lifespan, insuring an earlier death. Stem cells are thought to be the foremost uncultivated source for deterrence and healing of many diseases (see Chart 1). The process has shown new hope for many horrible degenerative diseases. Mice reproduced to show signs of Sandhoff disease, an adolescent disorder, implanted with stem cells revealed progress. Depleted levels of the Hexosaminidase trigger the disease. It was found that by implanting the stem cells it replenished the low levels rebuilding the dwindling amount. Additionally, with the help of stem cells scientists are initiating modern methods to regenerate brain cells used to treat Parkinsons disease. By replacing defective cells with...

References: China Post. (2007). Researchers join stem cell experiment on spinal injuries. July 8, 2008, from http://www.chinapost.comDevitt, T. (2007). Human Embryonic Research is Necessary. Detroit, MI: Greenhaven PressEve, D., Marty, D., McDermott, R., Klasko, S., & Sanberg, P. (2008, May-June). Stem Cell Research and Health EducationHaugen D., & Musser, S. (2007). Introduction to human embryo experimentation: At issueHeled, Yaniv. (2008, Wntr). On presidents, agencies, and the stem cells between them: a legal analysis of Preseident Bushs and the federal governments policy on the funding of research involving human embryonic stem cellsLindsay, R. (2008). Embryonic stem cell research is ethical. Detroit, MI: Greenhaven PressWalker, P. (2006, November 20). Stem cell cure for diabetes. Chemistry and Industry,11(1), 22Weiss, R. (2004, June 10). Stem cells an unlikely therapy for alzheimer 's. Washington Post, p

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Stem Cell Therapy Essay - 2136 Words

Helping Pets Heal Themselves!

Adult Stem Cell Therapy is a new innovative treatment option for dogs suffering from osteoarthritis, hip dysplasia or other joint related issues. Patients can be treated on an outpatient basis with their own stem cells collected, processed and administered the same day. Not only does stem cell therapy reduce pain and inflammation but it also restores quality of life and range of motion and regenerates tendons, ligaments and joint tissue.

Utilizing Adult Stem Cells is the wave of the future, says Zoran Djordjevich, DVM of Mohnacky Animal Hospital of Carlsbad, who has successfully treated numerous patients with great results. Owners are reporting their pets have made tremendous improvement and are enjoying a more active lifestyle. Dr George is currently using stem cells to enhance his advanced Canine Total Hip Replacement implant surgery as well, promoting faster healing in these patients. To find out more on how stem cell therapy can help your pet call us today!

Stem cell therapy is a procedure that harnesses the bodys innate regenerative and healing processes to treat diseases. The procedure at Mohnacky Animal Hospital uses adult stem cells isolated from your pets fat tissue, a rich source of stem cells. Studies have shown that these stem cells can develop into many different types of cells and tissues, including cartilage and bone. They also secrete many biological factors that promote healing. In a stem cell procedure, cells are isolated from a small amount of fat and then injected at the site of injury or disease. Cells are often given intravenously as well since stem cells have the ability to home to sites of injury and inflammation. In the treatment of osteoarthritis in joints, for example, stem cells can generate new cartilage and bone plus secrete potent anti-inflammatory factors, thereby replacing lost or damaged tissues, reducing pain, and increasing mobility.

Stem cell therapy uses the bodys own regenerative cells and the myriad of proteins (cytokines, growth factors) they produce to help the patient heal itself naturally. Stem cells treat the source of the problem by repairing damaged tissue and/or halting the disease process. Other medical treatments, such as anti-inflammatory drugs, generally address just the symptoms. With the advanced protocol used at Mohnacky Animal Hospital, over 95% of animals treated for osteoarthritis show significant improvement.

Stem cell therapy is considered quite safe. It uses the animals own stem cells so there is no risk of rejection. Minor surgery under anesthesia is required to collect the fat tissue. On a dog, this surgery is simpler than a spay, and is completed in about 20 minutes.

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Pet Stem Cell Therapy | Mohnacky Animal Hospitals in ...

What happens to my pet when they come in for stem cell therapy?

First, your vet will put your pet under general anesthesia. Then, she will make a small incision and collect 2-4 tablespoons of fat (either in the belly or behind the shoulder blades). MediVet provides on-site training this process ensures your pets cells are isolated and activated in the proper manner.

The surgical time requiring anesthesia is typically less than 30 minutes. The cells are isolated, activated and re-administered on site so your pet can go home that same day.

We recommend that the patient be limited to activity within the first 10 days. It is likely your pet will be feeling good and want to exert themselves, however we recommend limiting physical activity so the cells have the ability to work in repairing injuries. Improvements are typically seen within the first two weeks and continue to improve over the next few months. Veterinarians report responses from initial treatments lasting 18-24 months.

Rehabilitation Schedule

MediVets patented stem cell procedure allows us to isolate stem cells from your pets own fat tissue, activate them and reintroduce them directly into the damaged areas all in one visit. The goal of this revolutionary procedure is to provide a potent anti-inflammatory effect promoting cartilage and other tissue regeneration ultimately creating a healthier environment for the affected area. Most importantly, its an all-natural approach to healing without the adverse side effects. One example, in the case of arthritis, stem cells can become new cartilage cells, thus reducing pain and increasing mobility.

We typically see about 18-24 months of relief after the initial treatment and even longer when treatment is sought at earlier stages. Most pet owners choose to bank cells, so re-treatment is easy and cost effective. MediVet has banking facilities in Kentucky, Australia and Europe. If symptoms return, your vet merely requests a dose of cells from the bank, and injects them. No surgery is necessary.

Stem cell therapy for animals has been commercially available since 2004. MediVet pioneered in-clinic treatment options around 2010 and has now successfully treated thousands of animals globally.

Stem cells treat the source of the problem by becoming new tissue replacing damaged tissue. Other treatments, such as NSAIDs, merely attempt to reduce symptoms. The treatment is very low risk, because it uses the animals own stem cells. With MediVets technology in a recent study conducted by four independent Veterinarians over 95% of animals treated show improvement. For pet owners, there are two main advantages to MediVet.155 Canine Study

Our typical patient has osteoarthritis (hip dysplasia, degenerative joint disease, calcifications, common degeneration and inflammation), soft tissue injuries (cruciate injuries, tears, ruptures, inflammation) or needs accelerated healing of fractures. We know a lot about these conditions, and over 95% of these patients get better, with MediVets Stem Cell Therapy. We also treat other cases under compassionate use. We know less about these conditions, but are seeing some exciting results. Some of those conditions are: degenerative myelopathy, feline gingivitis, end-stage renal disease, liver and kidney failure, allergy, auto-immune, inflammatory bowel disease, pulmonary fibrosis, IMHA, atopy, and spine trauma. Our veterinarians would love to talk with you if you have questions about any of these conditions or would like to submit your pet for a compassionate use trial.

Yes, this procedure is very safe. The biggest risk as in any surgical procedure is using anesthetic, to remove the fat tissue. On a typical dog, veterinarians report this procedure is easier than a spay. The fat is collected in about 20 minutes. Processing the sample is done carefully by one of our highly trained veterinary technicians (fully trained by MediVet). In the thousands of animals treated by MediVet, they have not observed any significant negative side-effects from stem cell therapy.

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Stem Cell Therapy - FloridaWild Vet Hospital

Since its formation in 2002, VetStem Biopharma has endeavored to improve the lives of animals through regenerative medicine. As the first company in the United States to provide an adipose-derived stem cell service to veterinarians for their patients, VetStem pioneered the use of regenerative stem cells in veterinary medicine; VetStem holds exclusive licenses to over 70 patents including world-wide veterinary rights for use of adipose-derived stem cells.

In January of 2004 the first horse was treated with VetStem Regenerative Cell Therapy for a tendon injury that would normally have been career ending. By August 2007, 2,000 horses had been treated with their own healing stem cells with a high return to performance rate. By December of 2010, the number of horses treated reached 4,000.

Building on the success in equine cases, in 2005 VetStem began working with select veterinary clinics in treating dogs with osteoarthritis and orthopedic soft tissue injuries. In 2007, VetStem had the first published peer-reviewed blinded placebo controlled multicenter study showing a significant difference for stem cell treated dogs in OA of the hip. In May 2007 the company began offering stem cell services for the commercial treatment of dogs and cats, and by January of 2011 over 3,000 had undergone the therapy.

When VetStem began investigating the use of an animals own regenerative cells for healing tendon injuries and for easing the pain of osteoarthritis, this form of therapy was not a commonly accepted treatment modality. However, through VetStems in-person and online Credentialing Course nearly 5,000 veterinarians in the U.S. and Canada have been educated regarding the benefits of helping the body to heal itself with stem cells. The course covers topics ranging from current research in Regenerative Cell Therapy, to how to select appropriate cases, to adipose collection and stem cell injection techniques.

Looking to the future, VetStem is actively investigating stem cell therapy for immune-mediated and inflammatory diseases, as well as organ disease and failure. VetStem works with its human medicine partners in the hope that VetStems work in the veterinary field will lead to advances in human medical treatment, so that both animal and owner will reap the benefits of these efforts in the form of a markedly improved quality of life.

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VetStem the Company | The History of VetStem

Positron emission tomography (PET)imaging is aprocedure that, when combined with computed tomography (CT), help physicians to more accurately diagnose and manage disease, especially cancer.

PET detects changes in cellular metabolism (how active a cell is), often indicating the presence of disease. CT detects changes in the physical size or shape of a lesionand shows exactlywhere in the body the lesion is located. By combining these two imaging technologies into a single scanner, we are now able to more accurately detect cancer and pinpoint its location in the body.

Together, PET and CT can be very helpful, for example, in the preoperative staging of some cancer types and in localizing suspected cancer recurrence when standard tests are inconclusive. This type of information can help physicians improve treatment planning for individual patients.

Normal PET Scan Normal CTScan Fused PET/CTScan

Active cells such as malignant cancer cells will use sugar as an energy source. Inactive cells such as benign cells and scar tissue (both noncancerous) will not use sugar as an energy source.

In PET, a special type of sugar is combined with a safe radioactive component to produce the radioactive tracer called FDG (Fluorodeoxyglucose). Once injected into a vein, the tracer, which emits signals detected by the scanner, will be absorbed by malignant cells but will not be absorbed by benign cells and scar tissue. This will indicate whether or not a lesion could be cancerous.

Combined with the localizing abilities of CT, this information can be used, for example, to show a surgeon the exact location of a malignant lesion that needs to be removed.

Upon arrival to the Functional Imaging Department, you will be asked to complete a brief questionnaire. A technologist will take you to an examination room to explain the procedure and answer any questions you may have. Youwill thenreceive the tracer injection andbe asked to relax in the private exam room for approximately 60 minutes to allow the tracer to circulate throughout your body. When this "uptake" period is complete, we will take you to the scan room to begin imaging.

You will lie on the imaging table which will slowly move you through the scanner while collecting data. For most procedures, you will be able to listen to music during the scan. The scan itself will last approximately 20 - 40minutesdepending on the type of scan ordered by your physician.

Once the scan has been completed and reviewed for technical quality, the appointment concludes and you will be free to leave. The entire procedure, from the time you arrive atBC Canceruntil the time you leave, will last approximately 2hours. A report will be sent to your physician once the scan has been read by a radiologist at BC Cancer.

A PET/CT scan is considered a diagnostic procedure similar to those done in Radiology and Nuclear Medicine. With over 2 million PET scans having been performed worldwide to date, there have been no reports of any adverse reaction to the tracer. Although there is a small amount of radiation exposure involved in your PET/CT scan, the exposure level is small and within the acceptable limits mandated by Health Canada for these types of procedures.

Also, tracers used in PET/CT have very short half-lives meaning they don't remain in your body very long. Twenty-four hours after your PET/CT scan, we would not be able to take any more images because the tracer will have completely left your body.

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PET Functional Imaging - BC Cancer

Theres controversy surrounding the use of stem cells, particularly in humans. But stem cell therapy is being used to treat beloved pets. Here's how it works in animals.

What are stem cells?

In all animals, stem cells are like blank slates. They start out without any clear identity, but can divide and grow into many different types of cells, like muscle or blood cells.

What is stem cell therapy?

Stem cells are being used to treat illness and heal injuries in pets. They are injected into the body to repair muscles, joints, and ligaments that have been damaged by arthritis or injury. Some cancers are treated with stem cells taken from the pet's own bone marrow. And research is underway to test stem cells for diabetes treatment, and to treat animals that have lost control of their bladders.

Does stem cell therapy for pets work the same as in humans?

Yes. The basic idea is the same, but because there are fewer regulations for treating animals, stem cell therapy is used more often in pets than in humans.

How long have veterinarians been using this type of treatment?

Vets have been testing stem cell therapy in animals for about 10 years, but serious work has amped up in the past 4 or 5 years.

What does the procedure involve?

Stem cells are usually taken from the animals fat tissue or blood plasma. They're then separated out from other cells and put back in the animal, usually by injecting them directly into the problem area.

Does it work?

Right now, there are no big studies to show that stem cell therapy works in pets. All we have is anecdotal evidence, or stories from pet owners and veterinarians. Studies are underway to give us better insight into how effective stem cell therapy is in pets.

Are there any risks?

The biggest risk is your pet developing cancer. Studies are being done to see how to lessen it.

How much does it cost?

In pets, stem cell therapy usually costs between $2,000 and $3,000, but it can go much higher.

Where can I look into pet stem cell therapy?

Teaching hospitals are a great place to start your search. Here are a few:

SOURCES:

American Kennel Club Canine Health Foundation: Regenerative Medicine.

Burns, K. Journal of the American Veterinary Medical Association, published online Feb. 15, 2011.

National Institutes of Health: "Stem Cell Basics."

Shila K. Nordone, PhD, chief scientific officer, American Kennel Club Canine Health Foundation.

North Carolina State University College of Veterinary Medicine: "Oncology - Canine Bone Marrow Transplant."

FDA: "FDA Warns About Stem Cell Claims."

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Stem Cell Therapy for Pets - Pet Health Center

PALL VPET Veterinary Platelet Enhancement Therapy

VPET is a regenerative medicine system, available to veterinarians nationwide through VetStem Biopharma. This system provides a convenient means to concentrate platelets and their associated growth factors from an animal's own blood (10ml to 55ml) for use as platelet enhancement therapy.

Using VPET a veterinarian can have an injectable platelet concentrate rich in biologically active cytokines and growth factors ready in about 30 minutes (from blood collection to insitu injections).

V-PET Introduction

V-PET Brochure

V-PET Owner Handout

* 3x concentration for standard 40lbs dog, up to 7x concentration for standard horse.

A Rich Source of Autologous Growth Factors and Bio-Scaffolding

What is PRP?

VetStem Genesis CS-2 Instructions

Genesis PRP FAQs

In order to calculate the RPMs needed for your centrifuge please enter the radius of the rotor and enter the centimeters below. Need help measuring your rotor? Click here for instructions on how to measure your centrifuge rotor.

Enter your radius in cm:

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Platelet Rich Plasma: PRP | VetStem GenesisCS